Baylor College of Medicine (Baylor) has a heritage of more than a century of biomedical research. It is a leading global institution with initiatives that bring basic science, translational, and clinical researchers together across disciplines and specialties to discover fundamental insights into human health and disease.
Founded by Dr Malcolm Brenner, the Center for Cell and Gene Therapy (CAGT) at Baylor comprises laboratories with preclinical, translational, gene vector, and extensive clinical research programs.
University of North Carolina (UNC) Lineberger is one of the select academic centers in the United States with the scientific, technical and clinical capabilities to identify novel tumor targets and develop innovative CAR-T immunotherapy for patients. In 2015, UNC Lineberger Comprehensive Cancer Center recruited Gianpietro Dotti, MD and Barbara Savoldo, MD, PhD, in its pursuit of harnessing the power of the immune system to fight cancer. The two investigators bring more than a decade of experience in the use of T cell therapy for the treatment of cancer patients – with a particular focus on the design and implementation of CAR-T cells.
St. Jude Children’s Research (St Jude) Hospital leads the way the world understands, treats and cures childhood cancer and other life-threatening diseases, by advancing cures, and means of prevention for paediatric catastrophic diseases through research and treatment.
The goal of the partnership is to explore a new approach to cellular immunotherapy by targeting multiple tumor antigens with CARs using Tessa’s VST platform. This novel multi-CAR VST approach carries the potential to improve survival rates in children as well as reduce the chance of tumor escape, a phenomenon where cancer evolves to evade a successful treatment.
National Cancer Centre Singapore (NCCS) is a national and regional center of excellence in research, education and clinical services, and patient care.
It is the base for the largest number of oncologists, researchers, and clinician-scientists in Singapore, with research widely recognized by the international medical community. The community of onsite research staff work to resolve clinically relevant questions to cancer in Singapore and other countries in the region.
Peking Union Medical College Hospital (PUMCH) is a leading comprehensive hospital in China.
PUMCH and Tessa are working together to accelerate the research and development of next-generation cellular immunotherapies targeting some of the most common cancers in China. Both partners will jointly design and prepare clinical trials to test novel cell therapies, including therapies within Tessa’s clinical pipeline, in China.
The Agency for Science, Technology and Research (A*STAR) is Singapore’s lead public sector agency that spearheads economic oriented research to advance scientific discovery and develop innovative technology.
As a Science and Technology Organisation, A*STAR bridges the gap between academia and industry, and its research creates economic growth and jobs for Singapore, and enhances lives by contributing to societal benefits such as improving outcomes in healthcare, urban living, and sustainability.
A*STAR oversees 18 biomedical sciences and physical sciences and engineering research entities primarily located in Biopolis and Fusionopolis.
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